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PHARMACOEPIDEMIOLOGY AND INFECTIOUS DESEASES RESEARCH GROUP(PHEMI)

The Pharmacoepidemiology and Infectious Diseases research group (Institut Pasteur / UVSQ EA 4499 / Inserm U657)

Focuses its research activities on the effects of population exposure to anti-infectious agents, including: the risks of infection, bacterial resistance to antibiotics, and escape from vaccination.



This group investigates the interactions between human populations, antimicrobial drugs, and antimicrobial treatment escape by microbes at the population level, in both hospital and community settings. Their studies aim to evaluate the respective and combined impacts of cross-transmission, host-bacterium interaction (natural or induced by vaccination) and changes in the exposure of the population to antibiotics and vaccines.



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Currently, the group's studies are exploring the interaction between exposure of the population to anti-infectious agents and the risk of infectious diseases, taking into account the environmental context of infectious risk dynamics. To do so, they use a combination of ad hoc epidemiological investigations and population-wide databases, by applying refinement of statistical methods, applications of mathematical modeling (population dynamics), computer simulation, and methods of social-sciences.



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